What Causes Knee Pain in Females?

What Causes Knee Pain in Females?

Dr. Viraj Patel
Nov 21, 2025
Causes Knee Pain

Knee Pain is one of the most common complaints among women, and it can interfere with daily life, as well as long-term mobility. Most women search for effective Knee Pain Treatment in Ahmedabad, especially when they find it difficult to climb stairs, sit cross-legged, or walk. Knowing why knee pain happens is your first point on the journey to finding relief that may work for you. Females - Some of the causes of knee pain in females will be different when compared to males because of hormonal, structural and lifestyle differences.

1. Hormonal Changes Throughout Life

Women undergo hormonally induced changes with menstruation, pregnancy, the puerperium and menopause. These hormonal fluctuations, particularly in estrogen and relaxin, may loosen ligaments surrounding the knee joint.

When the ligaments become less taut, the knee becomes unstable and more susceptible to strain, pain, or sudden injury. Estrogen levels drop during menopause, which can also impact bone health and lead to women being more vulnerable to osteoarthritis and joint deterioration.

2. Female Body Structure Differences In Anatomy

Women have a wider pelvis, so the alignment of the thigh bone is different, and more pressure is placed on the knee joint. This discrepancy of alignment raises the Q-angle.

A larger Q-angle can be associated with problems such as patellofemoral pain syndrome, in which the kneecap doesn’t slide smoothly along its path. This frequently results in sudden onset pain around the front of the knee, particularly on bending, squatting, sitting for long periods or walking up and down stairs.

3. Overuse of Daily Activities

Many women juggle household chores, office jobs and sweating it out at the gym or fitness classes, but they are not aware that their knees take a beating for most of these activities. Running, jumping, standing for a long time or lifting weights too much can put stress on the knee joint.

Over time, this repetitive strain causes tendons to become inflamed, the kneecap gets irritated or, in extreme cases, the beginning of cartilage wear. Inappropriate shoes can even cause overuse injuries.

4. Osteoarthritis and Age-Related Wear

Osteoarthritis as a cause of knee pain is one of the most common in women, especially females who are over 40. That’s why women are more susceptible to it, especially with hormonal shifts, genetic predisposition and the way joints are put together.

The cushioning cartilage that keeps the knee protected thins out. Growing worse, movement becomes painful, swelling becomes more common, and stiffness is greater in the morning or after sitting too long.

5. Weight Gain and Stress on the Knee Joint

The excess body weight adds strain to the knees. The knees bear up to four times the load of every kg while walking.

Many women gain weight during pregnancy or after, when they are going through menopause, and if their weight isn’t controlled back then, it’s like adding pressure to a car that’s already out of balance. This can cause pain, swelling and difficulty bending the knee.

6. Vitamin and Mineral Deficiencies

It is not uncommon for females to have low levels of Vitamin D, calcium, and magnesium intake, all of which degrade bones and joints. Vitamin D deficiency can lead to muscle weakness and bone pain, both of which can increase the risk of wear and tear on the knees.

If you are not eating well or not maintaining a regular diet, that could also be the cause of taking a longer time to heal when the knee starts to hurt.

7. Injuries and Ligament Problems

Women are at greater risk of sustaining an Anterior Cruciate Ligament (ACL) injury. The rapid twisting, fast movements that occur when participating in sports or even a misplaced step during a walk can all result in ligament tears.

These injuries can cause swelling, instability and lingering knee pain if not treated at once.

Foot and Hip Alignment Issues

Sometimes the knee isn’t actually at fault. Flat feet, weak muscles in the hips or poor walking form can all affect knee alignment. If they don’t match, the knee has to work harder to make up the difference, and problems emerge over time.

Final Thoughts

In women, knee pain is often a combination of overuse and wear and tear, but it can be influenced by hormonal, structural or age-related issues across the board. The sooner you diagnose and treat it, the less likely that these kinds of injuries will affect your nightly activities. While our trainers at Aarunya Hospital offer conservative care, pain management is best addressed through a personalised body workout that includes exercises, nutrition counselling, lifestyle adjustments and medical consultation, working together to restore flexibility so they can move around as freely as they did before.